1. irritate

verb. (ˈɪrɪˌteɪt) Cause annoyance in; disturb, especially by minor irritations.
Synonyms
devil grate hassle harass harry annoy chevy molest displease rankle chivy beset rag bother rile antagonise get chevvy fret peeve vex get to nark ruffle eat into provoke antagonize chivvy gravel chafe nettle get at get under one's skin plague
Antonyms
please lend lose sell end
Etymology
irritate (English)
irritatus (Latin)
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2. irritate

verb. (ˈɪrɪˌteɪt) Excite to an abnormal condition, or chafe or inflame.
Synonyms
exacerbate rub gall fret exasperate chafe worsen aggravate scratch itch
Antonyms
better soothe attract satisfy like
Etymology
irritate (English)
irritatus (Latin)

3. irritate

verb. (ˈɪrɪˌteɪt) Excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus.
Synonyms
stimulate vellicate pinch excite
Antonyms
stifle praise calm refrain refuse
Etymology
irritate (English)
irritatus (Latin)
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