a state of depression so severe that the person loses contact with reality and suffers a variety of functional impairments
a sunken or depressed geological formation
a mental state characterized by a pessimistic sense of inadequacy and a despondent lack of activity
a long-term economic state characterized by unemployment and low prices and low levels of trade and investment
sad feelings of gloom and inadequacy
a state of depression and anhedonia so severe as to require clinical intervention
an air mass of lower pressure; often brings precipitation
characteristic of or suffering from psychosis
a person afflicted with psychosis
