1. trisomy

noun. chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell.


  • mongolism
  • chrosomal abnormality
  • Down's syndrome
  • Down syndrome
  • mongolianism
  • chromosomal aberration
  • chromosonal disorder
  • trisomy 21


  • -y (English)
  • -y (Middle English (1100-1500))
  • trisome (English)
  • -some (English)

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Sentences with trisomy

1. Adjective
Babies with trisomy 13 have a high mortality rate

2. Noun, singular or mass
Women over 40 may produce eggs with too many or two few chromosomes, which can result in conditions like Down syndrome or the spectrum of trisomy disorders.

3. Adverb
* Patau syndrome, or trisomy 13, which results from three

4. Verb, past tense
For instance, *trisomy* 21 (Down syndrome) is caused by an extra copy of chromosome 21 in the egg or sperm that results in the fertilized egg receiving three copies of chromosome 21.

5. Coordinating conjunction
 The chromosomal disorder has three copies of chromosome 21, called trisomy** 21.