1. scrapie

noun. a fatal disease of sheep characterized by chronic itching and loss of muscular control and progressive degeneration of the central nervous system.


  • -ie (English)
  • scrape (English)
  • scrapen (Middle English (1100-1500))

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Sentences with scrapie

1. Adjective
Goats affected with scrapie display behavioral and neurological changes.

2. Verb, 3rd person singular present
When farmers first noticed their sheep had an unusual disease affecting their brains, they named it scrapie without understanding that prions were behind the illness.

3. Noun, singular or mass
Today, scientists know that an infections protein or prion causes scrapie and mad cow disease.