noun. a genetic disorder of metabolism; lack of the enzyme needed to turn phenylalanine into tyrosine results in an accumulation of phenylalanine in the body fluids which causes various degrees of mental deficiency.
- ketonuria (English)
- phenyl (English)
Example sentences of the word phenylketonuria
1. Noun, plural
Dogs with a rare genetic disorder known as PKU or phenylketonuria can't process phenylalanine normally, causing toxic levels to build up in the blood stream.
2. Noun, singular or mass
Although this isn't a problem for most people, it can be a serious problem for people with a genetic disorder called phenylketonuria, or PKU, or other people with certain health issues.